Journal of Research in Medical Sciences

ORIGINAL ARTICLE
Year
: 2019  |  Volume : 24  |  Issue : 1  |  Page : 102-

Standardized Lycium chinense fruit extract enhances attention and cognitive function in healthy young people by a double-blind, randomized, placebo-controlled, crossover trial


Sun-Yong Chung1, Moonkyu Kang2, Seong-Bin Hong3, Hyunsu Bae2, Seung-Hun Cho1 
1 Department of Neuropsychiatry, College of Korean Medicine, Kyung-Hee University, Seoul, Korea
2 Department of Physiology, College of Korean Medicine, Kyung-Hee University, Seoul, Korea
3 Biomix Inc. 142 Ilsan-ro, Isandong-gu, Koyang, Kyunggi-do, Korea

Correspondence Address:
Dr. Seung-Hun Cho
Department of Neuropsychiatry, College of Korean Medicine, Kyung Hee University, 26, Kyungheedae-ro, Dongdaemoon-gu, Seoul 02447
Korea

Background: Lycium chinense fruit (LCF) is widely distributed in East Asia that has been used traditionally for antiaging purposes. This study was performed to examine the effects of LCF on attention and cognitive function in healthy young people. Materials and Methods: An 11-week, double-blind, randomized, placebo-controlled, crossover trial of 74 patients was conducted and its data were collected on Kyung-Hee University Korean Medical Hospital, Seoul, Korea. In crossover treatment, LCF or placebo was administered three times a day, total 3600 mg as two capsules of 600 mg once for 4 weeks with 3-week washout each. The computerized neurocognitive function test (CNT), the Korean version of the attention-deficit/hyperactivity disorder rating scale-IV, the clinical global impression rating scale, and the Frankfurt attention inventory (FAIR) for two groups were conducted 0 week before and 4 week, 11 week after the experiment, and significant mean changes of these tests for within group or two groups were measured by paired t-test or unpaired t-test. Results: The administration of LCF or placebo crossover for 8 weeks in healthy young people presented significant improvement in the verbal learning test, digit span forward test, digit span backward test, auditory continuous performance task of CNT, and FAIR-performance value compared with the placebo group (each group n = 43, P < 0.05). Conclusion: Thus, the consumption of LCF might be beneficial to increase learning and memory through attention and cognitive enhancing effect in normal young people, at an average age of 18 years of age.


How to cite this article:
Chung SY, Kang M, Hong SB, Bae H, Cho SH. Standardized Lycium chinense fruit extract enhances attention and cognitive function in healthy young people by a double-blind, randomized, placebo-controlled, crossover trial.J Res Med Sci 2019;24:102-102


How to cite this URL:
Chung SY, Kang M, Hong SB, Bae H, Cho SH. Standardized Lycium chinense fruit extract enhances attention and cognitive function in healthy young people by a double-blind, randomized, placebo-controlled, crossover trial. J Res Med Sci [serial online] 2019 [cited 2020 Nov 27 ];24:102-102
Available from: https://www.jmsjournal.net/article.asp?issn=1735-1995;year=2019;volume=24;issue=1;spage=102;epage=102;aulast=Chung;type=0