Journal of Research in Medical Sciences

ORIGINAL ARTICLE
Year
: 2018  |  Volume : 23  |  Issue : 1  |  Page : 61-

Clinical assessment of patients with acromegaly


Feyzi Gokosmanoglu1, Attila Onmez2 
1 Department of Endocrinology, Sakarya University Medicine Faculty, Sakarya, Turkey
2 Department of Internal Medicine, Duzce University Medicine Faculty, Duzce, Turkey

Correspondence Address:
Dr. Attila Onmez
Düzce Üniversitesi Tip Fakültesi, Yörükler Mah., Konuralp yerleşkesi, 81620 Merkez/Düzce
Turkey

Background: In this study, we aimed to retrospectively evaluate treatment outcomes and treatment methods in acromegaly patients. Materials and Methods: The study included 65 acromegaly patients followed in Sakarya University Faculty of Medicine Department of Endocrinology in Turkey between 2004 and 2013. Clinical, biochemical, and radiological data were obtained retrospectively from the medical files of the patients. All cases have been discussed in the endocrinology and pituitary surgery council, and a multidisciplinary treatment approach had been chosen in management. Results: Sixty-five patients were included in the study. Of the patients, 57% were female. Mean age was 45.3 ± 9.2 years old. Of the cases, 12.3% were microadenomas (n = 8, tumor diameter <10 mm) and 87.6% were macroadenomas (n = 57, tumor diameter ≥10 mm). In our study, 70% remission was achieved with the first operation and medical treatment. Patients with invasive acromegaly without remission after the first operation underwent reoperation, medical treatment, and conventional or stereotactic radiotherapy and achieved 45% remission rate. Conclusion: Pituitary surgery is the first treatment option for acromegaly. In patients who could not be remissioned after the first operation, remission can be achieved by combined therapy consist of reoperation, medical treatment, and conventional or stereotactic radiotherapy.


How to cite this article:
Gokosmanoglu F, Onmez A. Clinical assessment of patients with acromegaly.J Res Med Sci 2018;23:61-61


How to cite this URL:
Gokosmanoglu F, Onmez A. Clinical assessment of patients with acromegaly. J Res Med Sci [serial online] 2018 [cited 2021 Jan 22 ];23:61-61
Available from: https://www.jmsjournal.net/article.asp?issn=1735-1995;year=2018;volume=23;issue=1;spage=61;epage=61;aulast=Gokosmanoglu;type=0