Home
About us
Editorial board
Ahead of print
Browse Articles
Search
Submit article
Instructions
Subscribe
Contacts
Login
Advanced Search
Users Online: 402
» Articles published in the past year
To view other articles click corresponding year from the navigation links on the left side.
All
|
Case Report
|
Case Reports
|
Editorial
|
Erratum
|
Letter To Editor
|
Letters to Editor
|
Mini Review
|
Notice of Retraction
|
Original Article
|
Original Articles
|
Review Article
|
Review Articles
|
Short Communication
|
Short Communications
|
Systematic Review
Export selected to
Endnote
Reference Manager
Procite
Medlars Format
RefWorks Format
BibTex Format
Show all abstracts
Show selected abstracts
Export selected to
Add to my list
Review Article:
Vitamin D, the gut microbiome and inflammatory bowel disease
Seyed-Amir Tabatabaeizadeh, Niayesh Tafazoli, Gordon A Ferns, Amir Avan, Majid Ghayour-Mobarhan
J Res Med Sci
2018, 23:75 (23 August 2018)
DOI
:10.4103/jrms.JRMS_606_17
PMID
:30181757
Vitamin D has an important role in bone metabolism but recently has been recognized as an immunoregulator, and this has led to investigations on the effect of Vitamin D supplementation in various autoimmune diseases and its anti-inflammatory effects. There is some evidence that Vitamin D can regulate gastrointestinal inflammation. In addition, previous studies have shown that Vitamin D can affect the gut microbiome. The aim of this review is to evaluate the effect of Vitamin D on inflammatory processes, especially its relation to the inflammatory bowel disease (IBD) and gut microbiome. There is some evidence that Vitamin D can regulate gastrointestinal inflammation, with epidemiological studies showing that individuals with higher serum Vitamin D have a lower incidence of IBD, particularly Crohn's disease. Vitamin D changes transcription of cathelicidin and DEFB4 (defensin, beta 4) that can affect the gut microbiome. Several cell types of the immune system express Vitamin D receptor, and hence the use of Vitamin D in immune regulation has some potential. Furthermore, Vitamin D deficiency leads to dysbiosis of gut microbiome and reported to cause severe colitis. Vitamin D supplementation is low cost and available and can be a therapeutic option.
[ABSTRACT]
[HTML Full text]
[PDF]
[Mobile Full text]
[EPub]
[Citations (27) ]
[PubMed]
[Sword Plugin for Repository]
Beta
Advanced Search
Month wise articles
Figures next to the month indicate the number of articles in that month
2022
July
[
2
]
May
[
1
]
April
[
1
]
March
[
2
]
February
[
1
]
2021
October
[
2
]
September
[
3
]
August
[
1
]
July
[
2
]
June
[
2
]
May
[
2
]
March
[
4
]
February
[
3
]
2020
December
[
1
]
November
[
3
]
August
[
2
]
July
[
1
]
June
[
4
]
April
[
2
]
March
[
1
]
2019
December
[
1
]
October
[
2
]
August
[
2
]
July
[
1
]
May
[
1
]
April
[
3
]
March
[
1
]
February
[
1
]
January
[
2
]
2018
December
[
1
]
October
[
2
]
September
[
1
]
August
[
1
]
July
[
2
]
June
[
2
]
April
[
1
]
March
[
3
]
February
[
1
]
January
[
3
]
2017
December
[
1
]
November
[
1
]
Sitemap
|
What's New
Feedback
|
Copyright and Disclaimer
|
Privacy Notice
© Journal of Research in Medical Sciences | Published by Wolters Kluwer -
Medknow
Online since 9
th
February, 2015