|Serena Pelusi, Rosa Lombardi, Lorena Airaghi, Larry Burdick, Mario Rango, Alessandra Penatti, Silvia Fargion
J Res Med Sci 2016, 21:117 (7 November 2016)
We discuss here an uncommon condition of neurogenic hypotension in the context of immunoglobulin light chain (amyloid light-chain) amyloidosis. The most serious feature was autonomic nervous system impairment, mainly characterized by severe refractory orthostatic hypotension, which became progressively invalidating, forcing the patient to bed. Moreover, since the systemic involvement of the disease, the patient presented also diarrhea, dysphagia, asthenia, peripheral edema because of gastrointestinal, and kidney dysfunction. Eventually, the massive myocardial depression and infiltration led to a fatal outcome.