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SHORT COMMUNICATION
Year : 2016  |  Volume : 21  |  Issue : 1  |  Page : 81

A preliminary study on the potential of Mycoplasma pneumoniae to induce dyskaryotic change in respiratory epithelium in adult community-acquired pneumonia


1 Department of Respiratory Medicine, First Hospital of Tsinghua University, Beijing, China
2 Department of Respiratory and Critical Care Medicine, Peking University People's Hospital, Beijing, China
3 Department of Radiology, First Hospital of Tsinghua University, Beijing, China
4 Department of Pathology, First Hospital of Tsinghua University, Beijing, China

Correspondence Address:
Shu-Chang An
Department of Respiratory Medicine, First Hospital of Tsinghua University, 6 Jiuxianqiao 1st Road, Beijing - 100016
China
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1735-1995.192497

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Background: This study aimed to explore the cellular morphology of respiratory epithelium in Mycoplasma pneumonia (MpP) patients. Materials and Methods: The cast-off cell morphological findings from bronchoscopic brushings in MpP and community-acquired pneumonia (CAP) caused by typical pathogens were reviewed. Results: Compared with the CAP group, cellular dysplasia in respiratory tract epithelial brushings was significantly greater in MpP patients (P = 0.033). Conclusion: Unique biological characteristics and mechanisms of pathogenesis of Mycoplasma pneumoniae (Mp) may result in dyskaryotic changes in respiratory epithelium in adult MpP.


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