Journal of Research in Medical Sciences

: 2020  |  Volume : 25  |  Issue : 1  |  Page : 44-

Herbs that might be effective for the management of COVID-19: A bioinformatics analysis on anti-tyrosine kinase property

Won Sriwijitalai1, Viroj Wiwanitkit2,  
1 Private Academic Writer/Consultant, Bangkok, Thailand
2 Department of Community Medicine, Dr. DY Patil University, Pune, Maharashtra, India; Department of Tropical Medicine, Hainan Medical University, Haikou, China; Department of Biological Science, Joseph Ayobabalola University, Ikeji-Arakeji, Nigeria

Correspondence Address:
Dr. Won Sriwijitalai
RVT Medical Center, Bangkok

How to cite this article:
Sriwijitalai W, Wiwanitkit V. Herbs that might be effective for the management of COVID-19: A bioinformatics analysis on anti-tyrosine kinase property.J Res Med Sci 2020;25:44-44

How to cite this URL:
Sriwijitalai W, Wiwanitkit V. Herbs that might be effective for the management of COVID-19: A bioinformatics analysis on anti-tyrosine kinase property. J Res Med Sci [serial online] 2020 [cited 2020 Jul 4 ];25:44-44
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COVID-19 is an important new infectious disease that affects >150 countries worldwide. This respiratory infection is a public health emergency to be managed. As a new disease, there is limited knowledge of treatment. In general, many drugs are tests for possible efficacy in disease management. The widely used antiviral drugs include oseltamivir and anti-HIV drugs.[1] In medical science, there are also attempts to find herbs, natural products, which might be effective in the treatment of the coronavirus disease.[2] In the previous report, an important target that is useful for the treatment of coronavirus disease is tyrosine kinase.[3] Any herbs that pose anti-tyrosine kinase property might be useful for the treatment of COVID-19. Here, the authors perform a pharmacoinformatics study to search for herbs that have antipeptidase property and might be useful. Using the same database mining technique as in the referencing publication,[4] the PubMed database is used as a primary tool for data mining. According to data mining, there are at least herbs that present anti-tyrosine kinase properties and might be useful for the treatment of COVID-19. Those herbs are Hesperethusa crenulata,[5]Perilla frutescens,[6]Ephedra equisetina,[7]Shiraia bambusicola,[8]Panax ginseng[9] and Carthamus tinctorius L [Table 1].[10] Of interest, those herbs are the classical well-known herbs in East Asia, where the COVID-19first emerged. The present data mining is only to roughly include potential herbs for further studies on the possible usefulness in the management of COVID-19. Some of these herbs are already confirmed for their advantages in the management of viral respiratory infections. For example, E. equisetina and P. ginseng are confirmed for its anti-influenza property.[11],[12]{Table 1}

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