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SHORT COMMUNICATION
Year : 2019  |  Volume : 24  |  Issue : 1  |  Page : 35

Determination of antimicotic susceptibility pattern of Candida species isolated from patients with symptomatic candiduria


1 Research Center of Pediatric Infectious Diseases, Institute of Immunology and Infectious Diseases; Department of Infectious Disease, Rasul-e Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
2 Department of Microbiology, Faculty of Medicine; Microbiol Biotechnology Research Center, Iran University of Medical Sciences, Tehran, Iran
3 Department of Parasitology and Mycology, School of Medicine, Shahid Beheshti University of Medical Scienses, Tehran, Iran
4 Student Research Committee, Kerman University of Medical Sciences; Department of Medical Mycology and Parasitology, School of Medicine, Medical University of Kerman, Kerman, Iran
5 Center for Research and Training in Skin Disease and Leprosy, Tehran University of Medical Sciences, Tehran, Iran

Correspondence Address:
Dr. Azam Fattahi
Center for Research and Training in Skin Disease and Leprosy, Tehran University of Medical Sciences, Tehran
Iran
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jrms.JRMS_880_18

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Background: The present study was conducted to determine antimicotic susceptibility of Candida species (sp.) from patients with symptomatic candiduria. Materials and Methods: Identification of Candida sp. and determination of efficacy of most routine antifungals were done using polymerase chain reaction-restriction fragment length polymorphism method and E-test, respectively. Results: The results from susceptibility test reveal that caspofungin and amphotericin B have high antifungal activity against both albicans (100% and 96%, respectively) and nonalbicans (95.11% and 72.72%, respectively) isolates. Conclusion: The present study suggests that caspofungin and amphotericin B have the excellent ability to eradicate both Candida groups that showed decreased susceptibility to other compounds.


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