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Year : 2018  |  Volume : 23  |  Issue : 1  |  Page : 8

Prevalence of peptic ulcer in Iran: Systematic review and meta-analysis methods

1 Department of Community Medicine, Faculty of Medicine, Psychosocial Injuries Research Center, Ilam, Iran
2 Department of Gastroenterology, Faculty of Medicine, Ilam, Iran
3 Department of Pediatrics and Medicine, Faculty of Medicine, Ilam, Iran
4 Department of Nursing, Students Research Committee, Ilam, Iran
5 Department of Nursing, Faulty of Nursing and Midwifery, Ilam University of Medical Science, Ilam, Iran

Correspondence Address:
Mr. Hamed Tavan
Psychosocial Injuries Research Center, Ilam University of Medical Sciences; Department of Nursing, Faculty of Nursing and Midwifery, Ilam University of Medical Science, Ilam
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jrms.JRMS_1035_16

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Background: Peptic ulcer is a prevalent problem and symptoms include epigastria pain and heartburn. This study aimed at investigating the prevalence and causes of peptic ulcers in Iran using systematic review and meta-analysis. Materials and Methods: Eleven Iranian papers published from 2002 to 2016 are selected using valid keywords in the SID, Goggle scholar, PubMed and Elsevier databases. Results of studies pooled using random effects model in meta-analysis. The heterogeneity of the sample was checked using Q test and I2 index. Results: Total sample size in this study consist of 1335 individuals with peptic ulcer (121 samples per article). The prevalence of peptic ulcers was estimated 34% (95% CI= 0.25 – 0.43). The prevalence of peptic ulcers was 30% and 60% in woman and man respectively. The highest environmental factor (cigarette) has been addressed in 30% (95% CI= 0.23-0.37) of patients. The prevalence of Helicobacter pylori was estimated in 62% (95% CI= 0.49-0.75) of patients. Conclusion: The results of this study show that prevalence of peptic ulcers in Iran (34%) is higher that worldwide rate (6% to 15%). There was an increasing trend in the prevalence of peptic ulcer over a decade from 2002 to 2016.

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